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A list of antibodies used in these studies is provided in Table 2

Knowing the right doses and how to give them is important

Traditional Approaches to Cartilage Repair Conventional treatments for cartilage injury include: Physical therapy to strengthen muscles around the knee Anti-inflammatory medications to reduce pain and swelling Arthroscopic surgery to clean up damaged cartilage Microfracture surgery, which stimulates new cartilage growth by creating tiny holes in the bone While these methods can provide relief, they often produce fibrocartilage, a type of repair tissue that is less durable than natural cartilage

Immune checkpoint inhibitors (ICIs) are a class of anticancer drugs known as monoclonal antibodies that target receptors like anti-programmed death 1 (anti-PD-1), anti-programmed death-ligand 1 (anti-PDL-1) and the anti-cytotoxic T-lymphocyte-associated antigen 4 (anti-CTLA-4)